Production of the remake starring Aleksei Serebryakov is to begin next month.
Aleksei Serebryakov, known for his turn in the Golden Globe-winning film Leviathan, will play the lead in the Russian remake of the TV medical drama House.
The series will be produced by Leviathanproduction company Non-Stop Production, which also plans a remake of the sitcom Modern Family.
"For the Russian version of House, we have assembled a team of the best film and television professionals and we will do our very best to make our adaptation worthy of the original series," executive producer Sergey Melkumov said in a statement.
"With 177 original episodes available for adaptation, this has the potential to be a long-running success on [free-to-air network] Rossiya 1, just as the U.S. series has been for so many broadcast partners globally," added Hannah Worrall, NBCUniversal vp format sales and production.
Production on the series will begin in April, and the broadcaster is expected to announce a premiere date later this year.
Serebryakov, 51, is one of the biggest Russian stars of his generation. In addition to Andrei Zvyagintsev's Leviathan, he is known for Sergei Bondarchuk's The Ninth Company and Alexei Balabanov's Cargo 200.
Non-Stop also has Fyodor Bondarchuk's Stalingrad, Russia's highest-grossing locally produced movie of all time, among its credits.
The original version of House, starring Hugh Laurie, was hugely popular in Russia when it was first aired several years ago.